| Factors | Total no. of patients | With culture conversion | Univariate | Multivariate | ||||||
| No. | % | Hazard ratio | 95% | Hazard ratio | 95% | p-value | ||||
| TB treatment | ||||||||||
|
|
| With bedaquiline | 42 | 38 | 41.7 | 34 | 45.3 | 2.2 | (13 - 3.1) | <0.001 |
|
|
| Without bedaquiline | 100 | 72 | 72.0 | Reference group |
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| |
| Age | ||||||||||
|
|
| 18 - 34 | 56 | 43 | 76.8 | Reference group |
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| |
|
|
| 35 - 54 | 66 | 49 | 74.2 | 1.1 | (0.7 - 1.7) |
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| 55 - 64 | 20 | 18 | 90.0 | 1.6 | (0.9 - 2.8) |
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| Sex | ||||||||||
|
|
| Male | 88 | 67 | 76.1 | Reference group |
|
|
| |
|
|
| Female | 54 | 43 | 79.6 | 1.1 | (08 - 1.7) |
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| Employment status | ||||||||||
|
|
| Employed | 103 | 79 | 76.7 | 0.8 | (0.5 - 1.3) |
|
|
|
|
|
| Unemployed | 27 | 22 | 81.5 | Reference group |
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|
| |
|
|
| Unknown | 12 | 9 | 75.0 | 0.7 | (0.3 - 1.3) |
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| Social history | ||||||||||
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| Smoking |
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|
|
|
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| |
|
|
| No | 63 | 50 | 79.4 | 1.6 | (1.1 - 2.3) | 1.4 | (1.0 - 2.1) | 0.07 |
|
|
| Yes | 79 | 60 | 76.0 | Reference group |
|
|
| |
| Alcohol use | ||||||||||
|
|
| No | 71 | 55 | 77.5 | 1.5 | (1.1 - 2.3) |
|
|
|
|
|
| Yes | 71 | 55 | 77.3 | Reference group |
|
|
| |
| Substance use | ||||||||||
|
|
| No | 104 | 88 | 84.6 | 1.8 | (1.1 - 2.9) | 1.4 | (0.9 - 2.3) | 0.17 |
|
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| Yes | 38 | 22 | 52.6 | Reference group |
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|
| |
| History of TB treatment | ||||||||||
|
|
| New | 12 | 11 | 91.7 | 1.7 | (0.9 - 2.3) |
|
|
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|
|
| Retreatment | 130 | 99 | 76.2 | Reference group |
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|
| |
| Comorbidities (diabetes mellitus, renal insufficiency, liver disease, HV, and cancer) | ||||||||||
|
|
| No | 115 | 81 | 81.0 | 1.0 | (0.6 - 1.6) |
|
|
|
|
|
| Yes | 27 | 19 | 62.5 | Reference group |
|
|
| |
| Body mass index (BMI): Underweight | ||||||||||
|
|
| No | 95 | 64 | 75.8 | 1.0 | (0.7 - 1.5) |
|
|
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|
|
| Yes | 47 | 36 | 83.3 | Reference group |
|
|
| |
| Baseline smear result | ||||||||||
|
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| Negative |
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|
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| Positive |
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