Characteristics | Total | With bedaquiline | Without bedaquiline | p-value | ||||||
No. | % | No. | % | No. | % | |||||
All cases | 192 | 100 | 75 | 100 | 117 | 100 |
| |||
Age group |
|
|
|
|
|
| 0.71 | |||
|
| 17 - 34 | 80 | 41.7 | 34 | 45.3 | 46 | 39.3 |
| |
|
| 25 - 54 | 87 | 45.3 | 32 | 42.7 | 55 | 47.0 |
| |
|
| 55 - 65 | 25 | 13.0 | 9 | 12.0 | 16 | 13.7 |
| |
Employment history |
|
|
|
|
|
| 0.02 | |||
| Employed | 33 | 17.2 | 10 | 13.3 | 23 | 19.7 |
| ||
|
| Unemployed | 146 | 76.0 | 64 | 85.3 | 82 | 70.1 |
| |
|
| Unknown | 13 | 6.8 | 1 | 1.3 | 12 | 10.3 |
| |
| Sex |
|
|
|
|
|
| 0.57 | ||
|
| Male | 122 | 63.5 | 50 | 66.7 | 72 | 61.5 |
| |
|
| Female | 70 | 36.5 | 25 | 33.3 | 45 | 38.5 |
| |
| History of TB treatment |
|
|
|
|
| 0.65 | |||
|
| New | 17 | 8.9 | 8 | 10.7 | 9 | 7.7 |
| |
|
| Retreatment | 175 | 91.1 | 67 | 89.3 | 108 | 92.3 |
| |
Social historyb |
|
|
|
|
|
|
| |||
| Smoking |
|
|
|
|
|
| 0.03 | ||
|
| Yes | 89 | 46.4 | 31 | 41.3 | 58 | 49.6 |
| |
|
| No | 96 | 50.0 | 44 | 58.7 | 52 | 44.4 |
| |
|
| Unknown | 7 | 3.6 | 0 | 0 | 7 | 6.0 |
| |
| Alcohol use |
|
|
|
|
|
| <0.001 | ||
|
| Yes | 82 | 42.7 | 9 | 12.0 | 73 | 62.4 |
| |
|
| No | 103 | 53.6 | 66 | 88.0 | 37 | 31.6 |
| |
|
| Unknown | 7 | 3.6 | 0 | 0 | 7 | 6.0 |
| |
| Substance Use |
|
|
|
|
|
| <0.001 | ||
|
| Yes | 21 | 10.9 | 4 | 5.3 | 17 | 14.5 |
| |
|
| No | 147 | 76.6 | 71 | 94.7 | 76 | 65.0 |
| |
|
| Unknown | 24 | 12.5 | 0 | 0 | 24 | 20.5 |
| |
With comorbiditiesa,b |
|
|
|
|
|
| 1 | |||
|
| Yes | 157 | 81.8 | 61 | 81.3 | 96 | 82.1 |
| |
|
| No | 35 | 18.2 | 14 | 18.7 | 21 | 17.9 |
| |
Body mass index (abnormal)b |
|
|
|
|
| 0.94 | ||||
|
| No | 121 | 63.0 | 48 | 64.0 | 73 | 62.4 |
| |
|
| Yes | 71 | 37.0 | 27 | 36.0 | 44 | 37.6 |
| |
Baseline sputum test results |
|
|
|
|
|
| ||||
| Smear |
|
|
|
|
|
| 0.35 | ||
|
| Negative | 52 | 27.1 | 25 | 33.3 | 27 | 23.1 |
| |
|
| Positive | 135 | 70.3 | 46 | 61.3 | 89 | 76.1 |
| |
|
| Unknown | 5 | 2.6 | 4 | 5.3 | 1 | 0.9 |
| |
| Culture |
|
|
|
|
|
| <0.0001 | ||
|
| Negative | 36 | 18.8 | 24 | 32.0 | 12 | 10.3 |
| |
|
| Positive | 142 | 74.0 | 42 | 56.0 | 100 | 85.5 |
| |
|
| Unknown | 14 | 7.3 | 9 | 12.0 | 5 | 4.3 |
| |