HIV and Aging Parameters | Description | Value/Population Size (=100) | Rationale |
a | Rate at which children susceptible to TB become HIV+ TB-susceptible adults | 6.15E−05 | Aging rate to maintain constant population structure × childhood incidence of HIV |
b | Rate at which children susceptible to TB become HIV− adults susceptible to TB | 0.071424179 | Aging rate to maintain constant population structure × (1-childhood incidence of TB) |
c | Rate at which HIV− adults susceptible to TB become HIV+ adults susceptible to TB | 0.003234425 | Adult HIV incidence (new HIV cases per year/population size) |
d | Rate at which children with latent TB become HIV+ adults with latent TB | 6.15E−05 | Aging rate to maintain constant population structure × childhood incidence of HIV |
e | Rate at which children with latent TB become HIV− adults with latent TB | 0.071424179 | Aging rate to maintain constant population structure × (1-childhood incidence of TB) |
f | Rate at which HIV− adults with latent TB become HIV+ adults with latent TB | 0.003234425 | Adult HIV incidence (new HIV cases per year/population size) |
g | Rate at which children with active TB become HIV+ adults with active TB | 6.15E−05 | Aging rate to maintain constant population structure × childhood incidence of HIV |
h | Rate at which children with active TB become HIV− adults with active TB | 0.035712089 | Aging rate to maintain constant population structure × (1-childhood incidence of TB)/2 |
i | Rate at which HIV− adults with active TB become HIV+ adults with active TB | 0.003234425 | Adult HIV incidence (new HIV cases per year/population size) |
j | Rate at which adults with HIV− adults with active infectious TB become HIV+ adults with active TB | 0.003234425 | Adult HIV incidence (new HIV cases per year/population size) |
k | Rate at which children with active TB become adults with active infectious TB | 0.035712089 | Aging rate to maintain constant population structure × (1-childhood incidence of TB)/2 |
x | HIV mortality rate | 0.05 | Assumed mortality set to maintain constant population |
y | TB mortality rate | 0.08 | Assumed mortality set to maintain constant population |
μ | Background mortality rate | 0.03 | Assumed mortality set to maintain constant population |