| AE type |
| Injection Time (s) | |||
| Unknown (N = 275) | Once (N = 541) | Twice (N = 277) | Thrice or more (N = 459) | ||
| Any | n (%) | 8 (2.9) | 9 (1.7) | 55 (19.9) | 133 (29.0) |
| 95% CI | (1.3, 5.7) | (0.8, 3.1) | (15.3, 25.0) | (24.9, 33.4) | |
| Local | n (%) | 8 (2.9) | 9 (1.7) | 55 (19.9) | 133 (29.0) |
| 95% CI | (1.3, 5.7) | (0.8, 3.1) | (15.3, 25.0) | (24.9, 33.4) | |
| Local pain | n (%) | 3 (1.1) | 7 (1.3) | 43 (15.5) | 118 (25.7) |
| 95% CI | (0.2, 3.2) | (0.5, 2.6) | (11.5, 20.3) | (21.8, 30.0) | |
| Swelling | n (%) | 1 (0.4) | 1 (0.2) | 22 (7.9) | 64 (13.9) |
| 95% CI | (0.0, 2.0) | (0.0, 1.0) | (5.0, 11.8) | (10.9, 17.5) | |
| Bruising | n (%) | 0 | 1 (0.2) | 12 (4.3) | 32 (7.0) |
| 95% CI | (0.0, 1.3) | (0.0, 1.0) | (2.3, 7.4) | (4.8, 9.7) | |
| Nodules | n (%) | 2 (0.7) | 0 | 1 (0.4) | 1 (0.2) |
| 95% CI | (0.1, 2.6) | (0.0, 0.7) | (0.0, 2.0) | (0.0, 1.2) | |
| Local allergic reaction | n (%) | 1 (0.4) | 0 | 0 | 1 (0.2) |
| 95% CI | (0.0, 2.0) | (0.0, 0.7) | (0.0, 1.3) | (0.0, 1.2) | |
| Pruritis | n (%) | 1 (0.4) | 0 | 0 | 0 |
| 95% CI | (0.0, 2.0) | (0.0, 0.7) | (0.0, 1.3) | (0.0, 0.8) | |
| Ecchymosis | n (%) | 0 | 0 | 0 | 1 (0.2) |
| 95% CI | (0.0, 1.3) | (0.0, 0.7) | (0.0, 1.3) | (0.0, 1.2) | |
| Implant displacement or bulge | n (%) | 1 (0.4) | 0 | 0 | 0 |
| 95% CI | (0.0, 2.0) | (0.0, 0.7) | (0.0, 1.3) | (0.0, 0.8) | |
| Others (i.e. local heat, acnes) | n (%) | 0 | 0 | 0 | 3 (0.7) |
| 95% CI | (0.0, 1.3) | (0.0, 0.7) | (0.0, 1.3) | (0.1, 1.9) | |