|
|
|
Baseline |
4 weeks |
8 weeks |
| Pigmentation |
Placebo |
9.5 ± 2.9 |
14.0 ± 4.0 (1.0 ± 5.0) |
11.8 ± 4.7 (−1.3 ± 3.5) |
| Delphinol® |
11.0 ± 5.9 |
15.5 ± 6.0 (−0.3 ± 5.3) |
14.5 ± 9.8 (−1.3 ± 4.6) |
|
| Wrinkle number |
Placebo |
1.1 ± 0.8 |
1.1 ± 0.8 (0.0 ± 1.4) |
1.6 ± 1.2 (0.5 ± 1.1) |
| Delphinol® |
1.1 ± 0.8 |
1.0 ± 0.5 (−0.1 ± 0.6) |
1.3 ± 0.9 (0.1 ± 0.6) |
|
| Wrinkle length |
Placebo |
36.3 ± 17.8 |
32.5 ± 26.8 (−3.8 ± 19.0) |
23.5 ± 20.8 (−12.8 ± 12.3) |
| Delphinol® |
27.6 ± 18.1 |
39.4 ± 31.1 (11.8 ± 21.1) |
41.5 ± 23.5 (13.9 ± 24.5) |
|
| Texture |
Placebo |
45.8 ± 13.3 |
51.6 ± 12.6 (5.9 ± 9.9) |
58.4 ± 5.8 (12.6 ± 15.2) |
| Delphinol® |
53.9 ± 15.8 |
46.8 ± 10.7 (−7.1 ± 12.9) |
54.4 ± 7.5 (0.5 ± 13.5) |
|
| Oil content |
Placebo |
50.4 ± 7.8 |
43.1 ± 12.7 (−7.3 ± 10.1) |
47.0 ± 8.6 (−3.4 ± 9.3) |
| Delphinol® |
50.5 ± 8.6 |
46.9 ± 11.0 (−3.8 ± 9.6) |
45.9 ± 9.7 (−4.8 ± 8.9) |
|
| Water content |
Placebo |
86.4 ± 16.7 |
80.4 ± 17.3 (−6.0 ± 5.6) |
85.1 ± 13.3 (−1.3 ± 4.3) |
| Delphinol® |
91.3 ± 8.5 |
87.1 ± 10.4 (−4.1 ± 8.4) |
90.3 ± 10.0 (−1.0 ± 6.4) |
|
| TEWL |
Placebo |
9.9 ± 3.6 |
13.8 ± 5.5 (3.9 ± 4.2) |
11.6 ± 1.7 (1.7 ± 2.4) |
| Delphinol® |
11.4 ± 5.7 |
15.4 ± 6.2 (4.0 ± 3.8) |
13.4 ± 3.8 (2.0 ± 3.4) |
|
| Dermal thickness |
Placebo |
1313.4 ± 350.3 |
1152.0 ± 253.1 (−161.4 ± 195.7) |
1229.6 ± 315.7 (−83.8 ± 89.6) |
| Delphinol® |
1382.6 ± 384.3 |
1219.8 ± 392.3 (−162.9 ± 612.6) |
1152.0 ± 348.6 (−230.6 ± 328.4) |
|
| Elasticity |
Placebo |
88.3 ± 6.2 |
89.4 ± 4.5 (1.1 ± 7.7) |
87.1 ± 5.6 (−1.1 ± 10.2) |
| Delphinol® |
89.4 ± 5.2 |
91.1 ± 4.2 (1.8 ± 6.1) |
90.6 ± 3.8 (1.3 ± 5.9) |