Entry
Ir catalyst precursor
[mol %]
Ketone
Yield
[%]b
Ee
[%]c
1
Ir(acac)(cod) (28) [5]
6
90
85
2
28 [5]
7
80
90
3
28 [5]
12
65
92
4
[IrCl(cod)]2 (5) [2.5]
6
99
93
5d
5 [2.5]
7
79
91
6d
5 [2.5]
9
88
86
7
5 [2.5]
10
61
84
8d
5 [2.5]
12
74
91
|
| ||||
| Entry | Ir catalyst precursor [mol %] | Ketone | Yield [%]b | Ee [%]c |
| 1 | Ir(acac)(cod) (28) [5] | 6 | 90 | 85 |
| 2 | 28 [5] | 7 | 80 | 90 |
| 3 | 28 [5] | 12 | 65 | 92 |
| 4 | [IrCl(cod)]2 (5) [2.5] | 6 | 99 | 93 |
| 5d | 5 [2.5] | 7 | 79 | 91 |
| 6d | 5 [2.5] | 9 | 88 | 86 |
| 7 | 5 [2.5] | 10 | 61 | 84 |
| 8d | 5 [2.5] | 12 | 74 | 91 |