|
| Mediated by mast cells | Bradykinin-mediated. | |
| Acquired | Hereditary | ||
| Symptom onset rate | Minutes | Hours | Hours |
| Average age of disease onset | Anyone | 30 - 60 years old | 0 - 20 years old |
| Site affected | Face, neck | Lips, tongue, uvula, upper respiratory tract | Face, extremities, upper respiratory tract, gastrointestinal tract |
| Hives | Yes | No | No |
| Family history | No | No | Yes |
| Drugs related | NSAID | Angiotensin Converting Enzyme inhibitors, Angiotensin Receptor Blockers, gliptins, sacubitril | Angiotensin Converting Enzyme inhibitors, estrogens |
| Antihistaminic response | Adequate | Without response | Without response |