| Familial cold auto-inflammatory syndrome (FCAS) | Muckle-Wells Syndrome | CINCA/NOMID |
Clinical characteristics | Urticarial rash, fever, fatigue, chills, arthralgia, myalgia, conjunctivitis, keratitis, headache. | Urticarial rash, fever, fatigue, arthralgia, myalgia, arthritis, conjunctivitis, keratitis, uveitis, sensory hearing loss, headache. | Urticarial rash, fever, fatigue, arthralgia, myalgia, distal femur overgrowth, conjunctivitis, keratitis, uveitis, papilledema, sensory hearing loss, headache, aseptic meningitis, intracranial hypertension, developmental delay. |
Patterns of exacerbations | 12 - 24 h | 1 - 3 days | 1 - 3 days |