Parameter

Description

Unit

β

energy intake rate to body

1/day

α

half saturation constant for leptin energy intake reduction

μg/dL

c1

production rate of leptin from fat mass

μg/(kg * dL * day)

c2

production rate of insulin from fat mass

μg/(dL * day)

c3

half saturation constant of insulin secretion

kg

δ1

decay rate of fat mass

1/day

δ2

decay rate of muscle mass

1/day

δ3

decay rate of leptin

1/day

δ4

decay rate of insulin

1/day

δ5

decay rate of uric acid

1/day

ε1

rate of muscle mass reduction due to uric acid

dL (μg/day)

ε2

muscle mass reduction rate due to uric acid influence

dL (μg/day)

σ

production rate of uric acid from energy intake

mg/(dL * kg * day)

η

half saturation constant of uric acid excretion

μg/dL

γ1

constant rate of leptin influence on uric acid excretion

dL/μg

γ2

constant rate of insulin influence on uric acid excretion

dL/μg