No IBD

(n = 845,051)

CD

(n = 2416)

p-value

UC

(n = 1845)

p-value

AIDS

1035

0.12%

0

0.00%

--

0

0.00%

--

Alcohol Abuse

9655

1.14%

51

2.10%

0.051

41

2.22%

0.057

Anemia

28,085

3.32%

195

8.06%

<0.001

147

7.98%

<0.001

Rheumatoid Arthritis/Collagen Vascular Disease

6884

0.81%

50

2.05%

0.003

30

1.64%

0.080

Chronic Blood Loss

1567

0.19%

≤10

0.17%

0.944

15

0.83%

0.005

Congestive Heart Failure

9821

1.16%

44

1.83%

0.169

45

2.44%

0.023

Chronic Lung Disease

63,243

7.48%

208

8.62%

0.354

186

10.08%

0.055

Coagulopathy

7256

0.86%

29

1.20%

0.415

30

1.62%

0.112

Depression

38,962

4.61%

185

7.64%

0.001

179

9.70%

<0.001

Diabetes Mellitus

54,488

6.45%

175

7.26%

0.459

166

9.02%

0.052

Diabetes with Chronic

Complications

5907

0.70%

≤10

0.21%

0.195

≤10

0.54%

0.718

Drug Abuse

10,973

1.30%

30

1.23%

0.890

20

1.11%

0.747

Hypertension

180,280

21.33%

528

21.87%

0.769

537

29.10%

<0.001

Hypothyroidism

38,128

4.51%

145

6.02%

0.115

128

6.94%

0.031

Liver Disease

8805

1.04%

29

1.18%

0.755

69

3.73%

<0.001

Lymphoma

1279

0.15%

≤10

0.21%

0.753

0

0.00%

--

Fluid and Electrolyte Disorders

69,211

8.19%

374

15.47%

<0.001

293

15.90%

<0.001

Metastatic Cancer

1284

0.15%

≤10

0.21%

0.757

0

0.00%

--

Neurological Disease

14,172

1.68%

78

3.24%

0.007

30

1.64%

0.955

Obesity

70,452

8.34%

154

6.38%

0.113

149

8.10%

0.874

Paralysis

2418

0.29%

11

0.44%

0.532

0

0.00%

--

Peripheral Vascular Disease

8121

0.96%

20

0.82%

0.750

36

1.93%

0.058

Psychoses

12,536

1.48%

89

3.70%

<0.001

60

3.28%

0.005

Pulmonary Circulation Disorders

2531

0.30%

15

0.62%

0.206

≤10

0.46%

0.534

Renal Failure

13,371

1.58%

19

0.78%

0.144

41

2.20%

0.340

Solid Tumor without Metastasis

3755

0.44%

≤10

0.22%

0.472

18

0.98%

0.103

Peptic Ulcer Disease

68

0.01%

0

0.00%

--

0

0.00%

--

Valvular Disease

9206

1.09%

31

1.27%

0.708

52

2.84%

0.001

Weight Loss

5748

0.68%

83

3.42%

<0.001

45

2.46%

<0.001