Factor

Nanoparticles size

MSR = 32.6667

R² = 0.999

Drug recovered

MSR = 8.5443

R² = 0. 941

Effect

Std.Err.

p-value

Effect

Std.Err.

p-value

Mean/Interc.

358.89

1.91

0.0034

5.73

0.97

0.1073

PLGA (L)

26.00

4.67

0.1131

2.03

2.39

0.5508

PLGA (Q)

57.67

4.04

0.0445

2.88

2.39

0.3963

Cip-HCl (L)

−23.67

4.67

0.1239

−7.51

2.39

0.1958

Cip-HCl (Q)

−49.83

4.04

0.0515

−1.96

2.07

0.5169

PVA (L)

−92.33

4.67

0.0321

2.84

2.39

0.4449

PVA Q)

29.83

5.72

0.1205

−3.09

2.92

0.4823

PLGA (L) * Cip-HCl (L)

103.33

8.08

0.0497

−3.84

4.13

0.5234