|
| Factors | Composition parameters | Low level | Centre level | High level |
| 1 | X1 (%w/v) | Concentration of PLGA in organic phase (Chloroform) | 1.0 | 1.5 | 2.0 |
| 2 | X2 (%w/v) | Concentration of Cip-Hcl in inner aqueous phase (Distilled water) | 0.5 | 1.0 | 1.5 |
| 3 | X3 (%w/v) | Concentration of PVA in external aqueous phase (Distilled water) | 0.1 | 0.2 | 0.3 |