Miccoli (2004)

Mean Age 38, 1y



Extent of surgery in thyroglossal duct carcinoma: reflections on a series on a series eighteen cases. Thyroglossal duct neoplasm was represented by papillary carcinoma in 16 cases; thyroid histology demonstrated papillary carcinoma in 6 cases (33.3%).

Mazzaferri (2004)

Thyroid cancer in thyroglossal duct remnants: a diagnostic and therapeutic dilemma.

Peretz (2004)

Tyroglossal duct carcinoma in children.

Belnoue (2004)

4 cases od papillary thyroglossal duct: one patient needed a thyroidectomy fifteen years after the initial management of the PTDC; 2 patients were treated by a Sistrunk procedure associated with total thyroidectomy. A microscopic focus of papillary carcinoma without cyst wall invasion, can be managed bi Sistrunk procedure with the need for long-term follow-up. Treatment of all other thyroglossal duct papillary carcinoma should include thyroidectomy followed by radioactive iodine treatment.

Shahin (2005)

Thyroglossal duct cyst: a cytopathologic study of 26 cases.

Demir (2005)

2 cases micropapillary carcinoma was detected tyroid gland of both patients. Simultaneous existence of papillary carcinoma in the thyroid gland and thyroglossal duct cyst in two patients.

Plaza (2006)

Time to close the debate? 5 new cases and proposal of a definitive algorithm for treatment.

Kandogan (2008)


Papillary carcinoma with associated microcarcinoma of the thyroid and without cervical lymphonode metastasis. Tumor diameter 2 cm.

Berni Canani (2008)



2.5 cm thyroglossal duct with a 0.6 cm focus of follicular variant of papillary carcinoma. Papillary Carcinoma arising from a thyroglossal duct in a patient with thyroid hemiagenesis.



Torcivia (2010)





Total thyroidectomy after the complete excision of the cyst is currently the recommended treatment for the papillary carcinoma followed by a substitute hormonal therapy, were achieved. It was shows that a latent thyroid cancer could develop even 15 years after the initial excision of the thyroglossal cyst.



Park (2010)



Histopathological examination of the specimen revealed papillary carcinoma arising in the TGDC and papillary microcarcinoma of the thyroid gland without extrathyroidal extension. Surgeons should be aware of TGDC carcinoma during surgical planning and postoperative treatment and should differentiate this carcinoma from an anterior midline neck mass.


Kwon (2011)

Prymary thyroglossal duct cyst papillary carcinoma with cervical node metastasis.

Cincinati (USA)

Kim (2011)

SPECT/CT precisely localized neck iodine uptake. In small numbers of patients, treatment is affected. Spect/CT should be used when available in thyroid carcinoma patients. In three of 13 studies with neck uptake, SPECT/CT provided no useful additional information.

Al Ain

(Unite Arab Emirates)

Balalaa (2011)



Although the Sistrunk procedure is often regarded as adequate, controversies exist concerning the need for thyroidectomy depending on histopathological findings.



Gomi (2011)



Papillary carcinoma with extensive squamous metaplasia arising from thyroglossal duct cyst in an 11-years-old-girl.



Forest (2011)

TGDC: 9 patients, femal predominance, median age 44 years. A total thyroidectomy was performed in eight of nine patients; the median size carcinoma was 10 mm. And received radioactive iodine therapy and suppressive doses of thyroxine. A sistrunk therapy procedure is the minimum therapeutic procedure, coupled with a total thyroidectomy for higher-risk cancers.