Quito

(Ecuador)

Pacheco Ojeda

43 pts TDC: In 5 patients (12%) papillary carcinoma. Follow-up 23 month. A Sistrunk prodedure is usually curative

Casablanca

(Marocco)

Sahraoui (2000)

36

F

Sistrunk procedure.

Dedivitis (2000)

36

F

Papillary Carcinoma arising from a thyroglossal duct cyst. The main question is what to do with the thyroid gland, there still is controversy about thyroid removal for a papillary carcinoma, but the entire patient should receive suppressive doses of thyroid hormone.

Rome

(Italy)

D’Annibale (2000)

39

M

Most thyroid cancers at the time of surgery are confined to the thyroid gland, infiltrating the adjacent structures in approximately 20% of cases and the local-regional lymphonodes in 8 to 11.5%. Thyroid papillary carcinoma is multifocal in 21% of cases. The multifocal nature of the cancer makes total thyroidectomy mandatory at the same time as surgery is performed to remove the cyst.

Pittsburgh

(USA)

Branstetter

6 pts

CT appearance of thyroglossal duct carcinoma: carcinoma should be considere in thyroglossal duct cysts that have a mural nodule or calcification or both. Ages from 14 to 59 years.

California

(USA)

Doshi (2001)

14 pts

Large case series: long term follow-up incorporating clinical examination is manadatory.

New York

(USA)

Patel¹⁸ (2002)

57 pts

The addition of total thyroidectomy to Sistrunk operation did not have a significant impact on outcome (p = 0.1). The Sistrunk operation is adequate for most patients with incidentally diagnosed TGDC carcinoma in the presence of a clinically and radiologically normal thyroid gland. Results of adequate excision using the Sistrunk operation are excellent and the concept of risk-group should be used to identify patients, who would benefit from more aggressive treatment.

Ducic (2002)

Thyroglossal duct cysts in the elderly population.

Amsterdam (Holland)

Goslings (2002)

15

M

In 10% - 40% of the patients who undergo a subsequent thyroidectomy, malignant focuses are also found I the thyroid. In view of this multifocal occurrence and the fact that in most cases the diagnosis of carcinoma is only made after the operation, which often implies uncertainty about oncological radicalness, the authors advice to perform a near (-total) thyroidectomy as the standard procedure in case of thyriglossal duct carcinoma. After this adequate treatment with 131I should be given.

Foggia

(Italy)

Cignarelli (2002)

3 cases

Rapid growth of the cystic nass, and the presence of a mural nodule on US, especially with calcifications, must raise the physician’s suspicion for a cancer arising in TDC.

Aluffi¹³ (2003)

Two cases, currenttly, most authors agree about their primary origin ex novo from ectopic thyroid tissue in the ctst. In most cases the diagnosis of thyroglossal duct carcinoma (TD) is not mede until histopathological examination has been performed on a resected cyst without any suspected clinical sign of malignancy. The definition of the correct surgical treatment for these carcinomas is still controversial. Most authors maintain that resection of a TDC with the Sistrunk procedure can be considered oncologically adequate then dealing with a differentiated carcinoma without extracapsular invasion and/or lymphonode metastase and with a normal thyroid.

Duzce

(Turkey)

Ozturk (2003)

11

M

After a primary Sistrunk procedure, the cyst and tract extending to the forame caecum at the base of the tongue in continuity with the midportion of the hyod bone were resected.

Naghavi (2003)

28

M

We recommend that thyroglossal duct cyst with a microscopic focus of papillary carcinoma without cyst wall invasion be managed with Sistrunk procedure along with effective suppressant dose of thyroxine.