Parameters

Controls, n (%)

Cases, n (%)

p-value

Age (years)

57.5 ± 11.1

59.6 ± 12.8

0.054

Sex

Male

57 (47.5)

82 (62.1)

0.023

Female

63 (52.5)

50 (37.9)

Anthropometry

WC (cm)

84.4 ± 8.2

88.8 ± 14.6

0.026

HC (cm)

102.6 ± 10.9

102.0 ± 13.9

0.784

WHR

0.8 ± 0.1

0.9 ± 0.1

0.006

BMI (kg/m2)

23.4 ± 5.1

27.8 ± 4.7

<0.001

Haemodynamic

SBP (mmHg)

123.5 ± 4.5

168.9 ± 20.8

<0.001

DBP (mmHg)

77.1 ± 4.3

99.2 ± 16.3

<0.001

PP (mmHg)

46.4 ± 5.1

69.7 ± 10.6

<0.001

MAP (mmHg)

92.5 ± 3.7

122.4 ± 17.2

<0.001

Hypertension (yes) n, (%)

NA

120 (90.9)

Hypertension duration (years)

NA

7.1 (1.4 - 16.3)

Socio-demographic

Past alcohol status

73 (60.8)

66 (50.0)

0.234

Family history of HTN

60 (50.0)

36 (27.2)

0.009

Family history of CVD

3 (2.5)

12 (9.1)

0.148

Biochemical Assays

Log renin (pg/ml)

1.4 ± 0.1

1.8 ± 0.1

<0.001

Log aldosterone (pg/ml)

2.3 ± 0.2

2.9 ± 0.2

<0.001

Log ARR

0.9 ± 0.1

1.1 ± 0.2

<0.001

Total cholesterol (mmol/l)

5.2 ± 0.9

5.5 ± 1.4

0.088

Triglyceride (mmol/l)

1.5 ± 0.7

1.2 ± 0.4

0.007

HDL-cholesterol (mmol/l)

1.8 ± 0.3

1.2 ± 0.4

<0.001

LDL-cholesterol (mmol/l)

2.7 ± 0.9

3.9 ± 1.4

<0.001

FBG (mmol/l)

4.6 ± 0.7

4.9 ± 0.9

0.057