Protocol I

phase A

Protocol I

phase B

Protocol M

Protocol II

phase 1

Protocol II

phase 2

P

Hb (g/L)

SR

IR

8.8 (8.2 - 9.1)

9.1 (8.8 - 9.6)

8.4 (8.1 - 8.9)

8.7 (8.2 - 9.3)

10.29 ± 0.91

10.6 ± 0.91

12.7 ± 1.04

13.0 ± 1.17

9.4 (8.3 - 10.2)

9.0 (8.3 - 9.6)

>0.05

Leukocyte (×109/L)

SR

IR

2.67 (1.8 - 3.14)

2.38 (1.5 - 4.5)

2.10 (1.5 - 2.75)

1.87 (1.3 - 3.0)

3.05 ± 0.87

3.42 ± 1.09

4.61 (3.6 - 6.2)

3.92 (3.2 - 4.9)

1.78 (1.1 - 2.3)

1.88 (1.1 - 2.3)

>0.05

ANC (×109/L)

SR

IR

0.82 (0.4 - 1.0)

0.84 (0.4 - 1.1)

0.72 (0.5 - 1.1)

0.89 (0.5 - 1.3)

1.4 (1.0 - 1.64)

1.68 (1.1 - 2.0)

2.98 (2.1 - 4.3)

2.5 (1.98 - 3.3)

0.55 (0.3 - 0.9)

0.69 (0.4 - 1.1)

>0.05

PLT (×109/L)

SR

IR

124.8 (88.2 - 190.8)

117.7 (86.2 - 159.7)

104.4 (60.2 - 159.2)

123.8 (81.3 - 169.0)

201.2 ± 80.7

194.8 ± 59.0

194.5 (139.4 - 233.7)

163.7 (128.9 183.5)

157.8 ± 71.4

131.5 ± 84.7

>0.05

DND (days)

SR

IR

17.9 ± 10.5

18.2 ± 12.8

21.5 ± 7.3

20.7 ± 12.0

4 (0 - 14)

1 (0 - 5)

2 (0 - 10)

7 (1 - 11)

12.2 ± 7.1

11.4 ± 6.0

>0.05

FEN (n/%)

SR

IR

24 (22%)

20 (22%)

34 (31%)

30 (32%)

10 (9%)

4 (4%)

22 (20%)

20 (22%)

20 (18%)

18 (19%)

>0.05