Grade 1

Grade2

Grade3

Grade 4

Hb (g/L)

LLN - 10

8 - 10

<8

life-threatening anemia

ANC (×10⁹/L)

LLN - 1.5x1

1.5 - 1

1 - 0.5

<0.5

PLT (×10⁹/L)

LLN - 75

75 - 50

50 - 25

<25

AST and ALT (IU/L)

>ULN - 3XULN

3 - 5XULN

5 - 20xULN

>20xULN