Primarytumour (T)

TX

Primary tumour cannot be assessed

T0

No evidence of primary tumour

Tis

Carcinoma in situ

Tis (DCIS)

Ductalcarcinoma in situ

Tis (LCIS)

Lobularcarcinoma in situ

Tis (Paget’s)

Paget’s disease (Paget disease) of the nipple NOT associated with invasive carcinoma and/or carcinoma in situ (DCIS and/or LCIS) in the underlying breast parenchyma. Carcinomas in the breast parenchyma associated with Paget’s disease are categorised based on the size and characteristics of the parenchymal disease, although the presence of Paget’s disease should still be noted.

T1

Tumour ≤ 20 mm in greatest dimension

T1mi

Tumour ≤ 1 mm in greatest dimension

T1a

Tumour > 1 mm but ≤5 mm in greatest dimension

T1b

Tumour > 5 mm but ≤10 mm in greatest dimension

T1c

Tumour > 10 mm but ≤20 mm in greatest dimension

T2

Tumour > 20 mm but ≤50 mm in greatest dimension

T3

Tumour > 50 mm in greatest dimension

T4

Tumour of any size with direct extension to the chest wall and/or to the skin (ulceration or skin nodules)e

T4a

Extension to the chest wall, not including only pectoralis muscle adherence/invasion

T4b

Ulceration and/or ipsilateral satellite nodules and/or oedema (including peaud’orange) of the skin, which do not meet the criteria for inflammatory carcinoma

T4c

Both T4a and T4b

T4d

Inflammatorycarcinomaf

Regionallymphnodes (N)

NX

Regional lymph nodes cannot be assessed (e.g. previously removed)

N0

No regional lymph node metastases

N1

Metastases to movable ipsilateral level I, II axillary lymph node(s)

N2

Metastases in ipsilateral level I, II axillary lymph nodes that are clinically fixed or matted; or in clinically detectedk ipsilateral internal mammary nodes in the absence of clinically evident axillary lymph node metastases

N2a

Metastases in ipsilateral level I, II axillary lymph nodes fixed to one another (matted) or to other structures

N2b

Metastases only in clinically detectedk ipsilateral internal mammary nodes and in the absence of clinically evident level I, II axillary lymph node metastases

N3

Metastases in ipsilateral infraclavicular (level III axillary) lymph node(s) with or without level I, II axillary lymph node involvement; or in clinically detectedk ipsilateral internal mammary lymph node(s) with clinically evident level I, II axillary lymph node metastases; or metastases in ipsilateral supraclavicular lymph node(s) with or without axillary or internal mammary lymph node involvement

N3a

Metastases in ipsilateral infraclavicular lymph node(s)

N3b

Metastases in ipsilateral internal mammary lymph node(s) and axillary lymph node(s)

N3c

Metastases in ipsilateral supraclavicular lymph node(s)

Distant metastasis (M)

M0

No clinical or radiographic evidence of distant metastases

M1

Distant detectable metastases as determined by classic clinical and radiographic means and/or histologically proven > 0.2 mm