| No. | Feature Name | Description |
| 1 | Fatthm Score | Fatthm score determining the cancerous nature of SNP calculated from fatthm tool |
| 2 | SubPSEC | Substitution Position-Specific Evolutionary Conservation (subPSEC) Score |
| 3 | Pdeleterious | Probability that a given variant will cause a deleterious effect on protein function calculated by Panther tool |
| 5 | Total Energy | Total energy difference of wild and mutant type |
| 6 | Backbone HBond | The contribution of backbone Hbonds |
| 7 | Sidechain Hbond | The contribution of sidechain-sidechain and sidechain-backbone Hbonds |
| 8 | Vander Waals | Contribution of the Vander Waals |
| 9 | Electrostatics | Electrostatic interactions |
| 10 | Solvation Polar | Penalization for burying polar groups |
| 11 | Solvation Hydrophobic | Contribution of hydrophobic groups |
| 12 | Vander Waals clashes | Energy penalization due to Vander Waals’ clashes (interresidue) |
| 13 | Entropy side chain | Entropy cost of fixing the side chain |
| 14 | Entropy main chain | Entropy cost of fixing the main chain |
| 15 | Torsional clash | Vander Waals’ torsional clashes (intraresidue) |
| 16 | Backbone clash | Backbone-backbone Vander Waals. |
| 17 | Helix dipole | Electrostatic contribution of the helix dipole |
| 18 | Disulfide | Contribution of disulfide bonds |
| 19 | Electrostatic kon | Electrostatic interaction between molecules in the pre-complex |
| 20 | Partial covalent bonds | Interactions with bound metals |
| 21 | Energy ionisation | Contribution of ionisation energy |