| Mechanical | In vitro and in vivo porcine model results [2] | ||
| Options | Notes | Selection | |
| Devices | 14 NPWT systems or Redon drain | Wound filler or topical NP only | NPWT [10] |
| Wound filler | Foam or gauze | Foam and tissue Granulation [14]-[17] | Either [5] |
| Interface material | Impregnated gauze | No statistical studies | Inconclusive |
| Drainage conduit | Preforated or non-perforated | Within or on top of wound filler | Perforated [9] |
| NP magnitude | −25 mmHg to −400 mmHg | Tissue perfusion modulation | −50 [12] [18]-[20] to −80 mmHg [11] [15] [21] [22] |
| NP waveforms | Continuous, square, or triangular wave | Inconsistent results [23] [24] | Inconclusive |
| Treatment duration | Study duration only | - | Inconclusive |