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| Hand of Benediction (proximal median neuropathy definition) | Ulnar Claw |
| Nerve involved | Proximal median nerve lesion | Distal ulnar nerve lesion |
| Digits affected | 2nd + 3rd digits most affected | 4th + 5th digits affected |
| Presentation with an open palm and at rest | Normal | 4th + 5th MCPJs hyperextended 4th + 5th Interphalangeal joints flexed |
| Presentation when making a fist | 2nd + 3rd MCPJs hyperextended 2nd + 3rd Interphalangeal joints neutral | Normal |
| Additional signs | Wasting of the thenar eminence | Wasting of the hypothenar eminence and dorsal interossei |