Parameters

Genomics

Proteomics

Definition

The study of an organism’s entire genome, including genes, regulatory regions, and non-coding regions

The study of an organism’s entire set of proteins, including their structure, function, and interactions

Focus

Identification of genes and their function

Identification of proteins and their function

Key Techniques

DNA sequencing, genome-wide association studies, transcriptomics

Mass spectrometry, protein microarrays, protein-protein interaction analysis

Output

Identification of potential drug targets based on genetic variants and gene expression patterns

Identification of potential drug targets based on protein expression patterns and protein-protein interactions

Advantages

Provides a comprehensive view of an organism’s genetic makeup and potential drug targets

Identifies proteins that are actively involved in disease processes and may be more relevant drug targets than genes

Limitations

Identifying relevant genes and their functions can be challenging, as many genes have multiple functions and interact with each other

Protein identification and analysis can be complex and expensive, and it may be difficult to identify relevant proteins among the vast number of proteins in a cell or tissue

References

[23] [24]

[25] [26]