Parameters | Genomics | Proteomics |
Definition | The study of an organism’s entire genome, including genes, regulatory regions, and non-coding regions | The study of an organism’s entire set of proteins, including their structure, function, and interactions |
Focus | Identification of genes and their function | Identification of proteins and their function |
Key Techniques | DNA sequencing, genome-wide association studies, transcriptomics | Mass spectrometry, protein microarrays, protein-protein interaction analysis |
Output | Identification of potential drug targets based on genetic variants and gene expression patterns | Identification of potential drug targets based on protein expression patterns and protein-protein interactions |
Advantages | Provides a comprehensive view of an organism’s genetic makeup and potential drug targets | Identifies proteins that are actively involved in disease processes and may be more relevant drug targets than genes |
Limitations | Identifying relevant genes and their functions can be challenging, as many genes have multiple functions and interact with each other | Protein identification and analysis can be complex and expensive, and it may be difficult to identify relevant proteins among the vast number of proteins in a cell or tissue |
References | [23] [24] | [25] [26] |