| Morphological feature | ALL | Burkitt type of ALL |
| Cell size | Small or large, heterogeneous. | Large |
| Nuclear chromatin | Ranges from fine or clumped to variable among cells within a single case. | Fine and homogeneous |
| Nuclear shape | Occasional clefting or indentation common | Regular, oval to round |
| Nucleoli | Range from not visible or small and inconspicuous to large and prominent | Prominent, one or more |
| Cytoplasm amount | Variable from scant to abundant | Moderately abundant |
| Basophilia | Variable | Very deep |
| Vacuolation | Variable | Often prominent |