Features

Exosomes

Microvesicles

Apoptotic Bodies

Diameter

30 - 150 nm

50 - 1000 nm

1000 - 5000 nm

Appearance

cup - shape

cup - round shapes

variable shapes

Density in (Sucrose Gradient)

1.13 - 1.19 g/mL

1.04 - 1.07 g/mL

1.16 - 1.28 g/mL

Sedimentation

100,000 g

10,000 g

16,000 g

Marker Proteins

tetraspanins, Alix, TSG101

integrins, selectins, CD40 ligand

histones

Origin

Endosome budding into MVBs, fusion of MVB with cell membrane

Outward budding of cell membrane

Outward blebbing of apoptotic cell membrane

Composition

Protein, lipids, coding RNA, Noncoding RNA, DNA

Protein, lipids, cell organelles, coding RNA, noncoding RNA, DNA

Cell organelles, proteins, nuclear fragments, coding RNA, noncoding RNA, DNA