Modality | Biological Measure | Resolution | Cost in US$ | Clinical Development |
White light endoscopy | Surface Morphology and Vasculature | 1 mm | 4 - 13,000 | Standard of Care |
Fluorescence and Reflectance Spectroscopy | Redox Ratio, Collagen and Elastin Remodelling | 1 mm | 30,000 | Additive to Oral Exam, Bronchoscopy, Esophagoscopy, Colonoscopy |
Narrow Band Imaging | Neovascularization | 1 mm | 13,000 | Additive to Colonoscopy |
Optical Coherence Tomography | Mucosal Stratification and Subsurface Tissue Morphology | 5 - 15 microns | 40 - 100,000 | Clinical Approved in Ophthalmology, Clinical Trials in Other Organ Sites |
Confocal Endomicroscopy | Subsurface Tissue and Cell Morphology | 1 micron | 70,000 | Being Evaluated in Multiple Organ Sites |