Major manifestation | Minor manifestation |
Carditis | Fever |
Migratory polyarthritis | Arthralgia |
Sydenham’s chorea | Elevated acute phase reactants (ESR, CRP) |
Subcutaneous nodules | Prolonged PR interval on ECG |
Erythema marginatum |
|
Diagnosis is established if two major or one major + two minor plus ・ Supporting evidence of a recent group A streptococcal infection (positive throat culture or rapid antigen test, elevatedor increasing streptococcal antibody test) |