AKI is defined as any of the following:

1

2

3

Increase in sCr ≥ 0.3 mg/dl (≥26.5 μmol/L) within 48 hours, or

Increase in sCr ≥ 1.5 time baseline, which is kmown or presumed to have occurred within the prior 7 days; or

Urine volume < 0.5 mL/kg/h for 6 hours.

AKI is staged for severity according to the following criteria

Stage 1

Stage 2

Stage 3

1.5 - 1.9 times baseline OR

≥0.3 mg/dl (≥26.5 μmol/L) absolute increase in sCr

sCr ≥ 2.0 - 2.9 times baseline

sCR ≥ 3.0 times from baseline OR

Increase in sCr to ≥4.0 mg/dL (≥353.6 μmol/L) OR

Initiation of renal replacement therapy OR,

In patient < 18 years, decrease in eGFR to <35 mL/min per 1.73 m²

Urine volume < 0.5 mL/kg/h for 6 - 12 hours

Urine volume < 0.5 mL/kg/h for ≥12 hours

Urine volume < 0.3 mL/kg/h for ≥ 24 hours

OR

Anuria for ≥12 hours