1) Six or more café-au-lait macules (>0 - 5 cm at largest diameter in a prepubertal child or >1 - 5 cm in post-pubertal individuals) |
2) Axillary freckling or freckling in inguinal regions |
3) Two or more neurofibromas of any type or one or more plexiform neurfibromas |
4) Two or more Lish nodules (iris harmatomas) |
5) A distinctive osseous lesion (sphenoid wing dysplasia, lon-bone dysplasia) |
6) An optic pathway glioma |
7) A first degree relative with neurofibromatosis type 1 diagnosed by the above criteria |