Prognostic variables/Score | 0 | 1 | 2 | 4 | |
Age | <40 | ≥40 | - | - | |
Antecedent pregnancy | mole | abortion | term | - | |
Interval months from index pregnancy* | <4 | 4 - <7 | 7 - <13 | ≥13 | |
Pretreatment serum hCG (IU/ml)** | <103 | 103 - <104 | 104 - <105 | ≥105 | |
Largest tumor size (including uterus) | <3 cm | 3 - <5 cm | ≥5 cm | ||
Site of metastases | lung | spleen, kidney | Gastro-intestinal | brain, liver | |
Number of metastases*** | 0 | 1 - 4 | 5 - 8 | >8 | |
Previous failed chemotherapy | - | - | Single drug | 2 or more drugs |