Prognostic variables/Score

0

1

2

4

Age

<40

≥40

-

-

Antecedent pregnancy

mole

abortion

term

-

Interval months from index pregnancy*

<4

4 - <7

7 - <13

≥13

Pretreatment serum hCG (IU/ml)**

<103

103 - <104

104 - <105

≥105

Largest tumor size (including uterus)

<3 cm

3 - <5 cm

≥5 cm

Site of metastases

lung

spleen, kidney

Gastro-intestinal

brain, liver

Number of metastases***

0

1 - 4

5 - 8

>8

Previous failed chemotherapy

-

-

Single drug

2 or more drugs