Normal sleep

Sleepless

p

Number

14

16

Age

55.0 ± 6.98

59.5 ± 6.75

0.084

Gender

05:09 (55%)

02:14 (14%)

Antihypertensive medicine amount at the beginning

2.3 ± 1.08

2.2 ± 0.68

0.74

Years of education

7.2 ± 3.98

6.5 ± 3.42

0.56

Employment (proportion of housewives)

42%

50%

Marital status (married)

64%

43%

Number of chronic diseases

1.5 ± 0.53

1.3 ± 0.48

0.41

Smoking

0

0

Oral contraceptive

0

0

Sedentary lifestyle

71%

87%

Alcohol

0

0

Initial BMI (kg/m²)

29.8 ± 6.35

31.7 ± 6.81

0.44

Initial BMI (kg/m²)

29.6 ± 6.13

32.0 ± 6.78

0.32

SBP time 0

139.0 ± 13.39

146.7 ± 11.49

0.1

SBP time 1

155.4 ± 16.74

153.8 ± 12.44

0.77

SBP time 2

142.0 ± 16.83

142.4 ± 15.65

0.94

SBP time 3

138.1 ± 17.27

145.0 ± 14.90

0.25

SBP time 4

135.3 ± 16.40

144.4 ± 13.15

0.1

DBP time 0

79.1 ± 9.66

82.1 ± 9.79

0.41

DBP time 1

90.6 ± 12.88

85.6 ± 9.15

0.22

DBP time 2

86.8 ± 13.02

80.4 ± 13.71

0.2

DBP time 3

81.3 ± 11.69

82.0 ± 13.24

0.88

DBP time 4

80.3 ± 12.80

80.6 ± 13.37

0.96

HR Time 0

72.5 ± 15.02

72.9 ± 12.66

0.93

HR Time 1

73.5 ± 9.75

71.9 ± 11.34

0.68

HR Time 2

74.3 ± 10.35

69.7 ± 12.23

0.28

HR Time 3

73.9 ± 9.26

70.1 ± 10.82

0.32

HR Time 4

71.9 ± 10.17

69.2 ± 10.25

0.47

HAM-D time 1

25.1 ± 4.97

27.3 ± 5.88

0.27

HAM-D time 4

4.5 ± 3.52

11.4 ± 4.81

0.00012

Sleep score time 1

3.5 ± 2.17

4.1 ± 1.99

0.47

Sleep score time 4

0

2.5 ± 1.99

0

Δ time 4 - 1 time SBP

16.3 ± 14.54

7.1 ± 11.85

0.065

Δ time 0 - 1 time DBP

11.4 ± 8.04

3.4 ± 9.79

0.02

Δ time 1 - time 0 SBP

−20.0 ± 13.45

−9.4 ± 14.87

0.049

Δ time 1 - time 4 PAD

−10.2 ± 6.27

−5.0 ± 9.41

0.089

Remitting

12 (71%)

5 (29%)

Total 17

Non-remitting

2 (15%)

11 (85%)

Total 13

Escitalopram

8 (54%)

7 (46%)

Total 15

Placebo

6 (40%)

9 (60%)

Total 15