Escitalopram

Placebo

p

Number

15

15

Age

56.7 ± 6.14

57.6 ± 7.30

0.71

Gender (M:F)

03:12

04:11

Antihypertensive medicine dose at the study onset

2.1 ± 0.99

2.4 ± 0.74

0.31

Years of education

7.2 ± 3.53

6.4 ± 3.85

0.55

Employment (proportion of housewives)

53%

46%

Marital status (married)

66%

53%

Number of chronic diseases

1.3 ± 0.51

1.4 ± 0.51

0,92

Smoking

0

0

Oral contraceptive

0

0

Sedentary lifestyle

93%

66%

Alcohol

0

0

Initial BMI (kg/m²)

31.7 ± 5.85

29.9 ± 7.29

0.47

Initial BMI (kg/m²)

31.8 ± 5.79

29.9 ± 7.20

0.44

SBP time 0

144.0 ± 13.50

142.2 ± 12.47

0.70

SBP time 1

156.7 ± 14.64

152.4 ± 14.23

0.42

SBP time 2

145.6 ± 15.39

138.9 ± 16.28

0.25

SBP time 3

145.1 ± 17.62

138.5 ± 14.37

0.27

SBP time 4

140.1 ± 15.12

140.2 ± 15.83

0.97

DBP time 0

81.8 ± 9.67

79.6 ± 9.89

0.54

DBP time 1

88.4 ± 9.28

87.4 ± 13.05

0.8

DBP time 2

85.8 ± 11.91

80.9 ± 15.02

0.32

DBP time 3

84.2 ± 11.15

79.2 ± 13.31

0.27

DBP time 4

80.5 ± 12.06

80.4 ± 14.07

0.98

HR time 0

72.3 ± 13.62

73.1 ± 13.99

0.871

HR time 1

71.3 ± 8.62

74.1 ± 12.20

0.473

HR time 2

69.8 ± 8.12

73.9 ± 13.99

0.336

HR time 3

68.5 ± 8.16

75.2 ± 11.01

0.067

HR time 4

66.8 ± 9.62

74.1 ± 9.55

0.0460^*

HAM-D time 1

27.9 ± 4.86

24.7 ± 5.79

0.11

HAM-D time 4

8.2 ± 7.06

8.2 ± 3.48

1.00

Sleep score time 1

4.4 ± 1.84

3.2 ± 2.15

0.11

Sleep score time 4

1.8 ± 2.53

0.8 ± 0.91

0.16

Δ time 1 - time 0 SBP

12.7 ± 17.88

10.2 ± 8.34

0.63

Δ time 0 - 1 time DBP

6.5 ± 9.27

7.7 ± 10.48

0.74

Δ time 4 - 1 time SBP

−16.6 ± 16.15

−12.1 ± 13.91

0.42

Δ time 0 - 1 time DBP

−7.9 ± 9.29

−6.9 ± 7.70

0.77

Remitting

10 (58%)

7 (42%)

Total 17

Non-remitting

5 (38%)

8 (61%)

Total 13

Normal sleep

8 (57%)

6 (43%)

Total 14

Sleepless

7 (43%)

9 (56%)

Total 16