Variable

Hypofractionation arm

Conventional arm

Frequency

Percentage

Frequency

Percentage

1) Chemotherapy

Neoadjuvant

Adjuvant

46

129

26.3

73.7

16

50

24.2

75.8

2) Chemotherapy schedule

AC × 4 → Docetaxel × 4

AC × 4 → Paclitaxel × 4

TAC × 6

No chemotherapy

87

38

35

-

49.6

30.4

-

20

63

1

1

1

95

1.5

1.5

1.5

3) Radiation planning details

(i) Supraclavicular fossa radiation field treatment

(ii) Central lung distance

Upto 1.5 cm

1.5 - 2.5 cm

2.5 - 3.5 cm

>3.5 cm

171

135

38

2

-

97.7

77

-

22

1

66

50

15

1

-

100

75.5

23

1.5

-

4) Recurrence pattern

Recurrence

local recurrences [chest wall]

systemic recurrences

14

3

11

8

1.7

6.3

4

-

4

6

-

6

5) Systemic metastasis

Brain

Lung

Liver

Bone

Contralateral breast

4

4

2

1

-

2.3

2.3

1.1

0.6

-

-

2

1

-

1

-

3

1.5

-

1.5

6) Acute radiation reaction

(i) Acute dermatitis

grade 1

grade 2

grade 3

grade 4

18

9

4

2

10.3

5.1

2.2

1.1

19

7

7

1

28.8

10.6

10.6

1.5

(ii) Acute esophagitis

grade 1

grade 2

grade 3

grade 4

15

15

1

-

8.6

8.6

0.5

-

6

1

-

-

9.1

1.5

-

-

(iii)Acute pneumonitis

grade 1

grade 2

grade 3

grade 4

6

6

2

1

3.4

3.4

1.1

0.6

4

1

1

-

6.1

1.5

1.5

-