Patients’ characteristics | Total (n. = 121) | <500 (n. = 23) | ≥500 (n. = 98) | p-Value | <350 (n. = 10) | ≥350 (n. = 111) | p-Value |
Age: <10 years ≥10 years | 88 33 | 19 (21.60%) 4 (12.12%) | 69 (78.40%) 29 (87.88%) |
0.24 | 8 (9.10%) 2 (6.06%) | 80 (90.90%) 31 (93.94%) |
0.73 |
Sex Male Female | 70 51 | 15 (21.43%) 8 (15.69%) | 55 (78.57%) 43 (84.31%) |
0.43 | 6 (8.37%) 4 (7.84%) | 64 (91.43%) 47 (92.16%) |
1.0 |
TLC <50,000 cells/μl ≥50,000 cells/μl | 83 38 | 18 (21.69%) 5 (13.16%) | 65 (78.31%) 33 (86.84%) |
0.33 | 8 (9.64%) 2 (5.26%) | 75 (90.36%) 36 (94.74%) |
0.50 |
Mediastinal mass (119)* Present Absent |
15 104 |
3 (20%) 19 (18.27%) |
12 (80%) 85 (81.73%) |
1.0 |
0 10 (9.62%) |
15 (100%) 94 (90.38%) |
0.36 |
Immunophenotyping B-ALL T-ALL |
95 26 |
21 (22.11%) 2 (7.70%) |
74 (78.89%) 24 (92.30%) |
0.16 |
9 (9.5%) 1 (3.85%) |
86 (90.5%) 25 (96.15%) |
0.69 |
CNS involvement Yes No |
7 114 |
1 (14.29%) 22 (19.30%) |
6 (85.71%) 92 (80.70%) |
1.0 |
1 (14.29%) 9 (7.89%) |
6 (85.71%) 105 (92.11%) |
0.46 |
Early response RER SER |
106 15 |
21 (19.81%) 2 (13.33%) |
85 (80.19%) 13 (86.67%) |
0.74 |
8 (7.55%) 2 (13.33%) |
98 (92.45%) 13 (86.67%) |
0.36 |
Induction response CR not |
104 17 |
20 (19.33%) 3 (17.65%) |
84 (80.77%) 14 (82.35%) |
1.0 |
8 (7.70%) 2 (11.76%) |
96 (92.30%) 15 (88.24%) |
0.63 |