| High specificity version (98%/28%)c | Current commercial test (91%/40%)c | Low specificity version (80%/49%)c | ||||||||
Riska % | Frequencyb % | PPVd % | 100-NPVe % | RRf | PPVd % | 100-NPVe % | RRf | PPVd % | 100-NPVe % | RRf | |
LOW |
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0 - 5 | 15 | 26.4 | 1.8 | 14.3 | 10.2 | 1.7 | 6.2 | 3.9 | 1.0 | 3.7 | |
5 - 10 | 24 | 53.2 | 5.6 | 9.5 | 26.5 | 5.1 | 5.2 | 11.3 | 3.2 | 3.5 | |
MID |
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10 - 15 | 8 | 66.7 | 9.5 | 7.0 | 38.8 | 8.6 | 4.5 | 18.3 | 5.5 | 3.3 | |
15 - 20 | 7 | 74.8 | 13.5 | 5.5 | 48.5 | 12.3 | 4.0 | 25.0 | 8.0 | 3.1 | |
20 - 25 | 6 | 80.3 | 17.6 | 4.6 | 56.3 | 16.1 | 3.5 | 31.3 | 10.6 | 3.0 | |
25 - 30 | 4 | 84.2 | 21.8 | 3.9 | 62.8 | 20.0 | 3.1 | 37.3 | 13.4 | 2.8 | |
30 - 35 | 3 | 87.1 | 26.1 | 3.3 | 68.2 | 24.1 | 2.8 | 43.0 | 16.4 | 2.6 | |
35 - 40 | 3 | 89.4 | 30.6 | 2.9 | 72.7 | 28.3 | 2.6 | 48.5 | 19.7 | 2.5 | |
40 - 45 | 3 | 91.2 | 35.2 | 2.6 | 76.7 | 32.8 | 2.3 | 53.7 | 23.2 | 2.3 | |
45 - 50 | 3 | 92.7 | 39.9 | 2.3 | 80.1 | 37.4 | 2.1 | 58.7 | 27.0 | 2.2 | |
50 - 55 | 3 | 93.9 | 44.8 | 2.1 | 83.1 | 42.2 | 2.0 | 63.4 | 31.1 | 2.0 | |
55 - 60 | 3 | 95.0 | 49.8 | 1.9 | 85.7 | 47.1 | 1.8 | 68.0 | 35.6 | 1.9 | |
60 - 65 | 2 | 95.9 | 55.0 | 1.7 | 88.1 | 52.4 | 1.7 | 72.3 | 40.5 | 1.8 | |
HIGH |
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65 - 70 | 2 | 96.7 | 60.4 | 1.6 | 90.2 | 57.8 | 1.6 | 76.5 | 45.9 | 1.7 | |
70 - 75 | 2 | 97.4 | 66.0 | 1.5 | 92.1 | 63.5 | 1.5 | 80.5 | 51.8 | 1.6 | |
75 - 80 | 2 | 98.0 | 71.7 | 1.4 | 93.9 | 69.4 | 1.4 | 84.4 | 58.4 | 1.4 | |
80 - 85 | 2 | 98.5 | 77.6 | 1.3 | 95.4 | 75.7 | 1.3 | 88.1 | 65.8 | 1.3 | |
85 - 90 | 2 | 99.0 | 83.7 | 1.2 | 96.9 | 82.2 | 1.2 | 91.7 | 74.1 | 1.2 | |
90 - 95 | 2 | 99.4 | 90.1 | 1.1 | 98.2 | 89.0 | 1.1 | 95.1 | 83.4 | 1.1 | |
95 - 100 | 4 | 99.8 | 96.6 | 1.0 | 99.4 | 96.3 | 1.0 | 98.4 | 94.1 | 1.0 | |
% Up |
| 10.1 |
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| 10.4 |
|
| 7.6 |
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| |
% Down |
|
| 16.8 |
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| 15.5 |
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| 14.9 |
| |