IC₅₀ (µM)

B16-F10

HT-1080

Drug only

PDT^a

Effective ratio^b

Drug only

PDT^a

Effective ratio^b

Zinc Pc

0.023

0.015

1.5

0.068

0.0021

32.4

4TFEO-Pc

³50

31.8

³1.6

27.5

5.52

5.0

βCD-tBu-Pc

16.7

1.10

15.2

5.31

0.58

9.2

αCD-4TFEO-Pc

³50

1.29

³38.8

≥50

1.32

³37.9

βCD-4TFEO-Pc

³50

1.12

³44.6

≥50

0.32

³156

γCD-4TFEO-Pc

³50

1.25

³40.0

≥50

1.67

³29.9

Talaporfin

35.1

8.50

4.1

31.7

12.8

2.5