Parameters

Mean on D0

Mean on D14

P value

Difference

Weight of rats (g)

156 ± 4

182 ± 3

0.1

not significant

Creatinine (mg/L)

10.9 ± 2

8.5 ± 0.9

0.2

not significant

Transaminase AST (U/L)

147 ± 7

144 ± 5

0.9

not significant

Transaminase ALT (U/L)

101 ± 2

80.7 ± 2

0.1

not significant

Number of blood leukocytes (G/L)

11.1 ± 1.0

9.0 ± 1.0

0.4

not significant

Hemoglobin level (g/dl)

14.8 ± 0.1

14.9 ± 0.1

0.9

not significant

Number of blood platelets (G/L)

587 ± 40

612 ± 32

0.9

not significant