# of animal

Initial weight average g

Weight average g at end of the test

Weight gain

Tumor size average at end of the test mm3 ± STDEV

Control IV PBS

22

18.5

21.2

2.7

1474 ± 487

IV Dox 4 mg/kg

15

18.7

17.3

āˆ’1.4

816 ± 334

IV Dox 2 mg/kg

5

17.4

18.8

1.4

1126 ± 476

STID100

19

18.7

21.2

2.5

463 ± 330

STID102

10

18.9

20.9

2.0

1122 ± 270

Anova Analysis

P = 0.83

Between 4 test groups (IV-PBS, IV-Dox4 mg/kg, STID100, STID102)

P 2.961Eāˆ’6

Between 4 test groups (IV-PBS, IV-Dox4 mg/kg, STID100, STID102)

4.52Eāˆ’10

Between 4 test groups (IV-PBS, IV-Dox 4 m/kg, STID100, STID102