Associated Protein, mRNAs or miR | Findings | Effects |
miR-26b | mice with CLP | affected the antiviral response of the host |
miR-27a | in the lungs of septic mice | up regulated in the progression to shock |
miR-34a | in murine sepsis | Regulate vascular endothelial cell senescence |
miR-106a/b | in whole blood of mice | Promote phagocytosis of macrophages by targeting SIRPa [41] |
miR-126 | in murine sepsis | Attenuates the increase in plasma levels of cytokines and chemokines induced by sepsis |
NADPH oxidase | patients with diagnosis of septic shock | Improve dysfunction of heart and papillary muscles in patients with sepsis [42] |
miR-223 | in CLP mice | play an important role in MSC-induced cardioprotection in sepsis [43] |
MFG-E8 | rats by CLP | Reduce the level of inflammatory cytokines and increase the survival rate of experimental animals [44] |
ADMSC | patients with diagnosis of septic shock | Improve dysfunction of heart and papillary muscles in patientswith sepsis [45] |