|
| Cortisol dysfunction | Exaggerated adrenal response | ||
| TBI (n = 9) | SAH (n = 6) | TBI (n = 27) | SAH (n = 23) | |
|
| mean ± S.D | mean ± S.D. | mean ± S.D. | mean ± S.D. |
| Cortisol nmol/l |
|
|
|
|
| 0 min (6 - 10 am)a | 161 ± 85** | 63 ± 54** | 727 ± 124*** | 720 ± 237** |
| 0 min (10 am - 6 pm)b | 17 ± 0 | 116 ± 88 | 721 ± 330** | 665 ± 168** |
| 30 minc | 471 ± 61*** | 396 ± 116*** | 1208 ± 425*** | 1248 ± 214*** |
| GCS | 7.33 ± 1.9 | 7.33 ± 4.6 | 5.96 ± 2.8 | 7.43 ± 4.1 |
| Peak S100B (12 - 36 h) µg/l | 0.61 ± 0.7 | 0.36 ± 0.2 | 0.58 ± 0.9 | 0.83 ± 3.0* |
|
| median | median | median | median |
|
| (min - max) | (min - max) | (min - max) | (min - max) |
| GCS | 7 (4 - 11) | 6 (3 - 13) | 5 (3 - 13) | 6 (3 - 13) |
|
| n (%) | n (%) | n (%) | n (%) |
| Hunt & Hess |
|
|
|
|
| 1 |
| 0 (0) |
| 0 (0) |
| 2 |
| 0 (0) |
| 2 (9) |
| 3 |
| 3 (50) |
| 7 (30) |
| 4 |
| 2 (33) |
| 12 (52) |
| 5 |
| 1 (17) |
| 2 (9) |
| Fisher grade |
|
|
|
|
| 1 |
| 0 (0) |
| 0 (0) |
| 2 |
| 0 (0) |
| 2 (9) |
| 3 |
| 0 (0) |
| 5 (22) |
| 4 |
| 6 (100) |
| 16 (69) |
| DT scan |
|
|
|
|
| Cerebral contusions | 6 (67) |
| 20 (74) |
|
| Obliteration of the third ventricle or basal cisterns | 3 (33) |
| 10 (37) |
|
| Subarachnoid bleed | 8 (89) |
| 20 (74) |
|
| Midline shift > 5 mm | 1 (11) |
| 12 (44) |
|
| Subdural/epidural haematoma | 8 (89) |
| 24 (89) |
|
| Brain oedema | 4 (44)* |
| 7 (26) |
|
| Basilar skull fractures | 4 (44) |
| 14 (52) |
|
| Facial fracture | 2 (22) |
| 8 (30) |
|