USA [30] | 1980-2009 | 37 | 28 WLE 5 exenteration 5 EBRT, CT | Progression-free survival: 11.4 months, Overall survival: 19 months. |
USA [57] | 1970-2009 | 15 | WLE, EBRT, CT, IM | 2/15 alive over 8 years follow-up |
China [34] | 1970-2005 | 31 | 15 Surgery & IM 7 surgery 4 CT & IM 3 CT 2 no treatment | 35.5% recurrence; 32.3% 5 year survival |
USA [35] | 1976-1986 | 5 | 5 WLE 3 CT, IM | Time to recurrence 7 months; mean survival 31 months |
USA [36] | 1970-2002 | 26 | 7 exenteration 10 WLE 3 RH V; 1 V 3 EBRT only | Fifteen patients died of the disease (3 - 83 months) Four patients no evidence of disease (5 - 24 months) Four patients alive with disease (6 - 276 months) |
USA [37] | 1977-2001 | 35 | 10 WLE 2 V 10 RH V 2 exenteration 11 EBRT, 26 IM or CT | Median survival 20 months Surgical therapy: median survival 25 months Radiation therapy: median survival 13 months |
United Kingdom [50] | 1975-2000 | 9 | 2 EBRT 1 RH,V 6 WLE | Median survival 24 months (range 4 to 60 months) |
China [16] | 1979-1997 | 9 | 9 surgery, CT, IM | 20% 5-year survival; one long term survivor at 19 years |
USA [38] | 1990 | 10 | 10 surgery, EBRT, CT | Mean time to recurrence: 8 months Mean survival: 15 months |
Austria [39] | 1982-1996 | 14 | 7 biopsy 5 WLE 1 RH V 1 exenteration | Mean survival 10 months (range 1 - 153) 21% 5-year survival |
USA [40] | 1966-1996 | 7 | 2 WLE 2 WLE, EBRT 2 ICRT 1 exenteration | Median time to death 20 months (2 ot 48 months) All Dead of disease |
USA [41] | 1982-1996 | 13 | 5 V 9 WLE | 64% Estimated 5-year survival |
USA [42] | 1972-1992 | 8 | 4 conservative: WLE, CT, EBRT 4 Radical: exent, RH | 4 patients radical surgery: 75% 2-year survival 4 patients conservative surgery: 0% 2-year survival |
Italy [43] | 1969-1993 | 20 | 15 WLE | 15 evaluable patients; 2 died postoperatively All patients died of disease; median survival 19 months |
USA [44] | 1986-1992 | 4 | 4 exenteration | All underwent pelvic exenteration; One post operative death Three patients alive at 31-to 97 months |
Hong Kong [45] | 1978-1990 | 10 | 1 exenteration, CT 2 RH V 3 WLE 3EBRT ± CT | Five patients died 2 - 22 months Five patients median survival 18 months |
USA [46] | 1936-1988 | 15 | 3 WLE 2 RH V 5 V, vulvectomy 3 exenteration 2 EBRT | 17.4% 5-year survival Two patients survival more than 5 years |
Spain [47] | 1984, 1986 | 2 | 1 RH V 1 EBRT | Died at 4 and 6 months |
Sweden [48] | 1960-1984 | 26 | Not stated | 13% 5-year survival |
USA [49] | 1935-1976 | 19 | 7 RH V 8 WLE, EBRT 4 EBRT, ICRT | 21% 5-year survival One long-term survivor at 14 years |