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| Olanzapine (n = 578) | Non-olanzapine atypical antipsychotics | Typical antipsychotics | ||||||||||||||||||||||
| Overall* (n = 487) | Risperidone (n = 160) | Aripiprazole (n = 154) | Blonanserin (n = 67) | Quetiapine (n = 44) | Paliperidone (n = 40) | Overall (n = 24) | |||||||||||||||||||
| n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | ||||||||||
| CGI-S schizophrenia score | n | 578 | 487 | 160 | 154 | 67 | 44 | 40 | 24 | ||||||||||||||||
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| Mean (SD) | 4.9 | (0.9) | 4.8 | (0.9) | 5.0 | (0.9) | 4.7 | (0.8) | 4.7 | (0.8) | 4.9 | (0.9) | 4.9 | (0.9) | 4.7 | (0.8) | ||||||||
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| p-valueS) | 0.015 |
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| 4 | 240 | (41.5) | 230 | (47.2) | 63 | (39.4) | 83 | (53.9) | 34 | (50.7) | 19 | (43.2) | 17 | (42.5) | 11 | (45.8) | ||||||||
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| 5 | 165 | (28.5) | 137 | (28.1) | 42 | (26.3) | 43 | (27.9) | 23 | (34.3) | 12 | (27.3) | 12 | (30.0) | 9 | (37.5) | ||||||||
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| 6 | 144 | (24.9) | 108 | (22.2) | 52 | (32.5) | 24 | (15.6) | 9 | (13.4) | 11 | (25.0) | 9 | (22.5) | 4 | (16.7) | ||||||||
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| 7 | 29 | (5.0) | 12 | (2.5) | 3 | (1.9) | 4 | (2.6) | 1 | (1.5) | 2 | (4.5) | 2 | (5.0) | 0 | (0.0) | ||||||||
| BPRS total score | n | 354 | 308 | 103 | 101 | 49 | 22 | 21 | 14 | ||||||||||||||||
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| Mean (SD) | 60.3 | (15.5) | 58.5 | (14.2) | 61.8 | (15.4) | 58.4 | (13.2) | 54.9 | (13.2) | 59.0 | (13.1) | 56.0 | (11.8) | 54.3 | (15.2) | ||||||||
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| p-valueS) | 0.108 |
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| ≥20, <30 | 2 | (0.3) | 2 | (0.4) | 0 | (0.0) | 1 | (0.6) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | ||||||||
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| ≥30, <40 | 25 | (4.3) | 23 | (4.7) | 5 | (3.1) | 4 | (2.6) | 7 | (10.4) | 2 | (4.5) | 2 | (5.0) | 2 | (8.3) | ||||||||
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| ≥40, <50 | 70 | (12.1) | 57 | (11.7) | 20 | (12.5) | 22 | (14.3) | 8 | (11.9) | 3 | (6.8) | 3 | (7.5) | 3 | (12.5) | ||||||||
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| ≥50, <60 | 82 | (14.2) | 97 | (19.9) | 28 | (17.5) | 31 | (20.1) | 19 | (28.4) | 6 | (13.6) | 8 | (20.0) | 5 | (20.8) | ||||||||
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| ≥60, <70 | 81 | (14.0) | 60 | (12.3) | 16 | (10.0) | 22 | (14.3) | 7 | (10.4) | 8 | (18.2) | 6 | (15.0) | 2 | (8.3) | ||||||||
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| ≥70, <80 | 54 | (9.3) | 40 | (8.2) | 18 | (11.3) | 12 | (7.8) | 6 | (9.0) | 1 | (2.3) | 2 | (5.0) | 1 | (4.2) | ||||||||
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| ≥80, <90 | 26 | (4.5) | 25 | (5.1) | 13 | (8.1) | 8 | (5.2) | 2 | (3.0) | 2 | (4.5) | 0 | (0.0) | 1 | (4.2) | ||||||||
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| ≥90, <100 | 10 | (1.7) | 3 | (0.6) | 2 | (1.3) | 1 | (0.6) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | ||||||||
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| ≥100, <110 | 4 | (0.7) | 1 | (0.2) | 1 | (0.6) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | ||||||||
| BPRS positive score | n | 354 | 308 | 103 | 101 | 49 | 22 | 21 | 14 | ||||||||||||||||
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| Mean (SD) | 16.5 | (4.9) | 16.1 | (4.8) | 17.5 | (4.7) | 16.0 | (4.5) | 14.5 | (4.9) | 15.6 | (4.7) | 15.1 | (4.3) | 13.5 | (5.2) | ||||||||
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| p-valueS) | 0.225 |
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| <5 | 0 | (0.0) | 1 | (0.2) | 0 | (0.0) | 0 | (0.0) | 1 | (1.5) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | ||||||||
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| ≥5, <10 | 28 | (4.8) | 28 | (5.7) | 6 | (3.8) | 9 | (5.8) | 5 | (7.5) | 3 | (6.8) | 2 | (5.0) | 3 | (12.5) | ||||||||
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| ≥10, <15 | 100 | (17.3) | 87 | (17.9) | 23 | (14.4) | 28 | (18.2) | 21 | (31.3) | 5 | (11.4) | 5 | (12.5) | 5 | (20.8) | ||||||||
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| ≥15, <20 | 120 | (20.8) | 114 | (23.4) | 35 | (21.9) | 43 | (27.9) | 14 | (20.9) | 10 | (22.7) | 10 | (25.0) | 4 | (16.7) | ||||||||
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| ≥20, <25 | 87 | (15.1) | 67 | (13.8) | 34 | (21.3) | 18 | (11.7) | 7 | (10.4) | 3 | (6.8) | 4 | (10.0) | 1 | (4.2) | ||||||||
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| ≥25, <30 | 19 | (3.3) | 11 | (2.3) | 5 | (3.1) | 3 | (1.9) | 1 | (1.5) | 1 | (2.3) | 0 | (0.0) | 1 | (4.2) | ||||||||
| BPRS negative score | n | 354 | 308 | 103 | 101 | 49 | 22 | 21 | 14 | ||||||||||||||||
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| Mean (SD) | 10.4 | (3.8) | 10.6 | (3.5) | 10.7 | (3.8) | 10.6 | (3.4) | 10.5 | (3.6) | 10.0 | (3.3) | 11.0 | (2.1) | 12.0 | (3.3) | ||||||||
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| p-valueS) | 0.493 |
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| <5 | 29 | (5.0) | 14 | (2.9) | 4 | (2.5) | 5 | (3.2) | 3 | (4.5) | 1 | (2.3) | 0 | (0.0) | 0 | (0.0) | ||||||||