| Protein | Molecular Weight | Plasma Concentration | |||
| Classical Pathway |
|
|
|
| |
|
| C1q | 400,000 |
| 65 | μg/ml |
|
| C1r | 190,000 |
| 50 | μg/ml |
|
| C1s | 88,000 |
| 40 | μg/ml |
|
| C4 | 200,000 |
| 640 | μg/ml |
|
| C2 | 117,000 |
| 25 | μg/ml |
|
| C3 | 185,000 |
| 1400 | μg/ml |
| Alternative Pathway |
|
|
|
| |
|
| Factor B | 93,000 |
| 200 | μg/ml |
|
| Factor D | 23,000 |
| 2 | μg/ml |
|
| C3 | 185,000 |
| 1400 | μg/ml |
| Membrane Attack Pathway |
|
|
|
| |
|
| C5 | 200,000 |
| 80 | μg/ml |
|
| C6 | 128,000 |
| 75 | μg/ml |
|
| C7 | 121,000 |
| 55 | μg/ml |
|
| C8 | 154,000 |
| 55 | μg/ml |
|
| C9 | 79,000 |
| 60 | μg/ml |
| Regulatory Proteins |
|
|
|
| |
|
| C1 Inhibitor | 85,000 |
| 20 | μg/ml |
|
| C4b Binding protein | 570,000 |
| 250 | μg/ml |
|
| Carboxypeptidase N | 310,000 |
| 50 | μg/ml |
|
| Factor H | 150,000 |
| 500 | μg/ml |
|
| Factor I | 80,000 |
| 35 | μg/ml |
|
| Properdin | 180,000 |
| 25 | μg/ml |
|
| S-Protein | 71,000 |
| 600 | μg/ml |