Adverse effects n = 114

Patients n (%)

Any event

39 (34.21)

Application site reactions

23 (20.17)

Systemic events

16 (14.03)

Hallucinations

3 (2.63)

Depression

1 (0.87)

Dizziness

1 (0.87)

Syncope

2 (1.75)

Sleep disorders

4 (3.50)

Agitation

2 (1.75)

Impulsive control disorders

2 (1.75)