Group | Drug | Adverse effects |
First-line oral | Isoniazid | Nausea, vomiting, epigastric pain, hepatotoxic, psychosis, convulsive seizures, mental confusion, and coma etc. |
Rifampin | Exanthema, hepatotoxicity, immunological reactions, nausea, anorexia, abdominal pain, fatigue, dizziness, headache, dyspnea, and ataxia etc. | |
Pyrazinamide | Nausea, vomiting, anorexia, severe exanthema, pruritus, rhabdomyolysis with myoglobinuria, kidney failure, acute arthritis in gouty individuals and hepatotoxicity. | |
Ethambutol | Retrobulbar neuritis, nausea, vomiting, abdominal pain, hepatotoxicity, hematological symptoms, hematological symptoms and hypersensitivity etc. | |
Second-line drugs | Aminoglycosides | Ototoxic, neurotoxic, nephrotoxic, neuromuscular blockage and hypersensitivity. |
Fluoroquinolones | Affects that gastrointestinal, central nervous system, musculoskeleta, cardiovascular system, urinary tract, endocrine system and also cause skin reactions and allergies. | |
Oral bacteriostatic second-line anti-TB drugs | Neurological adverse effects (headache, vertigo, dysarthriasomnolence, convulsion, mental confusion, and memory deficit) and psychiatric adverse effects (psychotic states with catatonic, paranoid, and depressive reactions, with a risk of suicide. |