Group

Drug

Adverse effects

First-line oral

Isoniazid

Nausea, vomiting, epigastric pain, hepatotoxic, psychosis, convulsive seizures, mental confusion, and coma etc.

Rifampin

Exanthema, hepatotoxicity, immunological reactions, nausea, anorexia, abdominal pain, fatigue, dizziness, headache, dyspnea, and ataxia etc.

Pyrazinamide

Nausea, vomiting, anorexia, severe exanthema, pruritus, rhabdomyolysis with myoglobinuria, kidney failure, acute arthritis in gouty individuals and hepatotoxicity.

Ethambutol

Retrobulbar neuritis, nausea, vomiting, abdominal pain, hepatotoxicity, hematological symptoms, hematological symptoms and hypersensitivity etc.

Second-line drugs

Aminoglycosides

Ototoxic, neurotoxic, nephrotoxic, neuromuscular blockage and hypersensitivity.

Fluoroquinolones

Affects that gastrointestinal, central nervous system, musculoskeleta, cardiovascular system, urinary tract, endocrine system and also cause skin reactions and allergies.

Oral bacteriostatic second-line anti-TB drugs

Neurological adverse effects (headache, vertigo, dysarthriasomnolence, convulsion, mental confusion, and memory deficit) and psychiatric adverse effects (psychotic states with catatonic, paranoid, and depressive reactions, with a risk of suicide.