Reactants 1 | Reactants 2 | Product | Yield % (time/min)a | Physical state mp (˚C) (mp litt.) | ||
X | R |
| 1/4 CEC | 1/2 CEC | 3/4 CEC | |
NH | H | | 95 (25) | 82 (30) | 80 (60) | 285 (286 - 289) [41] |
NH | NO2 | 3b | 87 (30) | 78 (50) | 70 (60) | 298 (297 - 299)[41] |
NH | OMe | | 96 (20) | 93 (40) | 73 (60) | 226 (226 - 227) [41] |
NH | Me | 3d | 94 (30) | 92 (50) | 78 (70) | 275 (275 - 276) [41] |
NH | OH | 3e | 95 (30) | 90 (40) | 70 (50) | 242 (240 - 242) [42] |
NH | Cl | | 89 (30) | 83 (60) | 69 (60) | 301 (301 - 303) [41] |
NH | F | | 90 (30) | 86 (40) | 84 (50) | 244 (249 - 251) [43] |
s | H | | 86 (40) | 70 (50) | 65 (90) | 112 (114 - 115) [44] |
s | NO2 | 4b | 80 (35) | 78 (65) | 70 (90) | 226 (226 - 227) [44] |
s | OMe | | 90 (40) | 81 (60) | 60 (100) | 122 (122 - 124) [44] |
s | Me | 4d | 90 (45) | 76 (55) | 78 (90) | 85 (85 - 86) [44] |
s | OH | 4e | 84 (45) | 80 (70) | 70 (90) | 224 (220 - 224) [45] |
s | Cl | | 78 (40) | 80 (70) | 69 (90) | 116 (116 - 118) [44] |
s | F | | 88 (40) | 78 (70) | 64 (90) | 102 (101 - 103) [44] |