Grading of tumor regression in non-small cell lung cancer, Junker et al., 2001

Grading I

No tumor regression or only spontaneous tumor regression in the sections of the primary lesion and mediastinal lymph nodes

Grading IIa

Morphologic evidence of therapy-induced tumor regression with at least 10% residual tumor cells in the sections of the primary lesion and/or mediastinal lymph nodes presenting more than focal microscopic disease

Grading IIb

<10% residual tumor cells in the sections of the primary lesion and/or mediastinal lymph nodes presenting focal microscopic disease

Grading III

Complete tumor regression with no evidence of vital tumor tissue in the section of the primary lesion and mediastinal lymph nodes