S

[9]

RL34A_ SCHPO

rpl34a

60S ribosomal protein L34-A

3

1

85

0.0408

536,330

R

[8]

RS23_ ASPFU

rps23

40S ribosomal protein S23

3

3

48

0.0033

1.85

S

[10]

RS9_ PODAN

RPS9

40S ribosomal protein S9 (S7) -

2

1

50

0.0001

89.76

R

[11]

HEX1_ EMENI

HexA

Woronin body major protein

Associated with the septal pores, role in translation regulation (ribosome binding)

3

1

97

0.0011

1.15

R

[8]

RL17_ ASPFU

rpl17

60S ribosomalprotein L17

7

7

355

0.0409

1.36

Stress response

R

[1]

[12]

[13]

[14]

[15]

[16]

B0XRX3

Afu2g09290

antigenic mitochondrial protein HSP60, putative (Chaperonin Cpn60 family)

Ÿ Cpn60 molecular sequencing is applied for barcoding

Ÿ Fungal Hsp60 can act as immunodominant antigens and facilitate powerful immunological properties; Vaccination with recombinant Hsp60 from the dimorphic fungi Histoplasma capsulatum and Paracoccidioides brasiliensis induced protection against these mycotic infections

Ÿ It is suggested that fever can activate Hsp60 gene expression of fungi in the human body and subsequently modify immunoregulatory processes; possible pathogenetic relevance

Ÿ Molecular chaperonins participate in nucleotide excision repair by maintaining repair proteins in their properly folded state. For another chaperonin, Hsp90, it has been demonstrated that CAG repeat stability is modulated by this chaperone protein. A decrease in Hsp90 levels results in nearly tenfold increases in the rate of contraction of a CAG repeat tract, while not affecting the rate of point mutations. As severe environmental stresses can overwhelm Hsp90 function, Hsp90 may be playing a role in mediating an influence by the environment on TR mutation rates.

2

2

60

0.0170

1.11

S

B0Y8B3

Afu6g10700

Chaperonin, putative (10 kda heat shock mitochondrial, Cpn10, Hsp60 family)

2

2

66

0.0330

3.98

S

[1]

[16]

[17]

B0XXV2

Afu3g10490

DNA damage response protein (Dap1)

S. cerevisiae ortholog Dap1p is required for cell cycle progression following damage and is involved in sterol regulation. Dap1p directs resistancetoitraconazole and fluconazole.

2

2

112

0.0229

10.26