First cycle

Second cycle

Patients (n)

334

436

Age (years) (mean ± SD)

<2 years

2 - 5 years

5 - 8 years

8 - 12 years

6.2 ± 2.2

32 (9.6%)

91 (27.2%)

120 (40%)

91 (27.2%)

7.0 ± 2.9

29 (6.7%)

104 (23.8%)

160 (36.7%)

143 (32.8%)

Boys: Girls, Boys (%)

174/160, 52%

235/201, 54%