Total population

<50 years

50 - 70 years

˃70 years

p-value

Male

Female

p-value

Number of patients included

2982

17.9%

(535)

56.2%

(1677)

25.8%

(770)

83.3

(2483)

16.7

(499)

Female

16.7%

(499/2982)

15.1%

(81/535)

14.4%

(241/1677)

23.0%

(177/770)

<0.0001

Average age

(years)

63

45

61

74

<0.0001

62

(52 - 70)

67

(54 - 74)

<0.0001

Post-acute CR, AHB/AR

(%)

98.8

98.3

98.6

99.5

98.7

98.8

CR-initiation (%)

Hospital

GP

Cardiologist

Patients

66.6

0.9

11.8

20.5

75.1

1.3

2.1

21.3

68.1

0.8

9.1

21.7

57.0

0.9

24.4

17.3

<0.0001

ns

<0.0001

<0.05

68.6

0.9

10.1

20.1

56.3

1.0

20.2

22.0

<0.0001

ns

<0.0001

Ns

CR diagnoses (%)

Post ACS

Post CABG

Post valve repair

ICD

PAD with vascular surgery

59.9 (1710/2854)

17.1 (489/2854)

8.4 (241/2854)

0.9 (25/2854)

1.2 (33/2854)

70.9 (360/508)

7.5 (38/508)

8.1 (42/508)

1.2 (6/508)

0.8 (4/508)

60.3 (970/1608)

18.3 (294/1608)

7.2 (116/1608)

0.9 (15/1608)

1.4 (22/1608)

51.5 (380/738)

21.3 (157/738)

11.3 (84/738)

0.5 (4/738)

0.9 (7/738)

<0.0001

<0.0001

<0.01

ns

ns

59.2

18.5

8.5

0.9

1.0

63.5

10.2

8.4

0.6

1.9

ns

<0.0001

ns

ns

ns

History of risk factors:

Physical inactivity

Diabetes

Genetic disposition

Lipid disorder

Hypertension

Smoking

Psychosocial stress

Overweight

33.9 (968/2854)

22.4 (639/2854)

32.6 (930/2854)

78.4 (2238/2854)

73.4 (2094/2854)

46.7 (1334/2854)

14.5 (413/2854)

46.7 (1333/2854)

44.7 (227/508)

10.2 (52/508)

38.2 (194/508)

69.2 (352/508)

54.3 (276/508)

70.9 (360/508)

24.4 (124/508)

53.7 (273/508)

36.0 (579/1608)

23.4 (377/1608)

32.3 (520/1608)

80.2 (1290/1608)

74.2 (1193/1608)

49.8 (800/1608)

15.9 (255/1608)

49.4 (794/1608)

22.0 (162/738)

28.5 (210/738)

29.3 (216/738)

80.8 (596/738)

84.7 (625/738)

23.6 (174/738)

4.6 (34/738)

36.0 (266/738)

<0.0001

<0.0001

<0.01

<0.0001

<0.0001

<0.0001

<0.0001

<0.0001

34.0

22.1

31.2

78.5

72.7

48.7

13.9

47.9

33.4

24.0

39.5

77.9

76.8

37.0

17.5

40.9

ns

ns

<0.001

ns

ns

<0.0001

<0.05

<0.01

Risk factors as

evaluated at CR start:

Fasting glucose

Total cholesterol

LDL cholesterol

HDL cholesterol

Triglycerides

Systolic blood pressure

Diastolic blood pressure

Actual smoking (%)

Depression at admission

(HADS ≥ 11) (%)

Anxiety at admission

(HADS ≥ 11) (%)

BMI (kg/m2)

111.7 ± 43.0

183.5 ± 44.5

107.5 ± 37.7

44.8 ± 13.2

165.3 ± 92.6

127 ± 20.4

76.9 ± 11.1

14.6 (365/2498)

9.2 (166/1801)

14.0 (253/1802)

28.4 ± 4.6 (97.9%)

99.8 ± 34.0

190.1 ± 44.4

112.7 ± 36.1

44.1 ± 14.4

177.5 ± 100.9

121.3 ± 16.7

77.5 ± 11.2

28.7 (140/487)

12.9 (45/348)

20.9 (73/349)

28.5 ± 5.0 (98.3%)

113.6 ± 43.2

183.6 ± 45.0

107.4 ± 38.4

44.3 ± 12.8

169.3 ± 97.8

127.9 ± 20.4

77.8 ± 10.9

14.4 (209/1454)

9.4 (98/1043)

13.8 (144/1,042)

28.7 ± 4.8 (98.5%)

117.8 ± 47.7

178.8 ± 43.1

104.3 ± 36.8

46.3 ± 13.1

148.0 ± 70.0

131.8 ± 20.7

74.5 ± 11.1

2.9 (16/557)

5.6 (23/410)

8.8 (36/411)

27.9 ± 3.9 (96.2%)

<0.0001

<0.0001

<0.0001

<0.0001

<0.0001

<0.0001

<0.0001

<0.0001

<0.001

<0.0001

<0.05

111.8 ± 43.1

181.0 ± 43.8

106.3 ± 37.2

43.2 ± 11.8

166.8 ± 95.4

127.3 ± 20.2

76.9 ± 11.1

14.8 (313/2,111)

8.7 (130/1496)

12.6 (189/1,505)

28.5 ± 4.5

111.0 ± 42.4

196.0 ± 45.9

113.1 ± 39.8

52.6 ± 16.7

157.8 ± 76.6

130.1 ± 21.9

76.8 ± 11.0

13.4 (52/387)

11.8 (36/305)

21.8 (66/303)

28.1 ± 5.4

ns

ns

ns

<0.0001

ns

<0.05

ns

ns

0.09

<0.0001

<0.05