| Group | Associated anomalies | Inheritance |
1 | Scalp ACC without multiple anomalies | Cleft lip and palate, tracheoesophageal fistula, patent ductus arteriosus, omphalocele, mental retardation, polycystic kidneys | Autosomal dominant or sporadic |
2 | Scalp ACC with limb abnormalities | Limbs reduced, syndactyly, clubfoot, encephalocele, nail dystrophy or absence, persistent cutis marmorata | Autosomal dominant |
3 | Scalp ACC with skin/organoid nevi | Epidermal nevi, corneal opacities, sclera dermoids, eyelid colobomas, mental retardation, seizures | Sporadic |
4 | ACC overlying embryologic malformations | Meningomyelocele, spinal dysraphia, cranial stenosis, leptomeningeal angiomatosis, gastroschisis, congenital midline porencephaly, ectopia of ear, omphalocele | Depends upon underlying condition |
5 | ACC with fetus papyraceus or placental infarcts | Single umbilical artery spastic developmental delay, spastic paralysis, clubbed hands and feet, amniotic bands | Sporadic |
6 | ACC associated with epidermolysis bullosa | Blistering of skin and/or mucous membranes, deformed nails, pyloric or duodenal atresia, abnormal ears and nose, ureteral stenosis, renal anomalies, amniotic bands | Depends upon type of epidermolysis bullosa |
7 | ACC localized to extremities without blistering | None | Autosomal dominant or recessive |
8 | ACC caused by teratogens | Imperforate anus (methimazole), other signs of intrauterine infection with varicella or herpes simplex | Not inherited |
9 | ACC associated with congenital syndromes | Trisomy 13, 4p-syndrome, ectodermal dysplasia, focal dermal hypoplasia, amniotic band disruption complex, XY gonadal dysgenesis, Johanson-Blizzard syndrome | Depends upon Syndrome |